Kusajili – Centralise les essais cliniques mondiaux

A Study to Evaluate MEDI0562 in Combination With Immune Therapeutic Agents in Adult Subjects With Advanced Solid Tumors The purpose of this study is to evaluate MEDI0562 in combination with immune therapeutic agents in adult subjects with select advanced solid tumors.

• Pays Australia, France, Netherlands, United States,
• Organes Aucun
• Spécialités Aucun

Validation of Nicom Device to Measure Stoke Volume Variation The purpose of this study is to evaluate the ability of NICOM (Noninvasive cardiac output monitor) to detect stroke volume variation induced by leg raising or fluid expansion during surgery

• Pays France,
• Organes Aucun
• Spécialités Aucun

Safety and Efficacy of BKM120 in Relapsed and Refractory NHL This is a phase II study evaluating the safety, tolerability and efficacy of BKM120 in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL) or follicular lymphoma (FL).

• Pays Belgium, France, Germany, Italy, Korea, Republic of, Spain, Turkey, United States,
• Organes Aucun
• Spécialités Aucun

Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing The purpose of this study is to assess the psychological, cognitive and social resources of applicants for Huntington's Disease and Presymptomatic Testing.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Predictive Clinical and Biological Parameters in Gynecological Cancer - GC-BIO-IPC 2013-010 Research of predictive clinical and biological factors in breast cancer : genomic, proteomic, mutation

• Pays France,
• Organes Aucun
• Spécialités Aucun

Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients at Early Stage of the Disease The purpose of this study is to evaluate the efficacy, safety and tolerability of PF-06649751 in Parkinson's disease patients at early stage of the disease.

• Pays France, Germany, Israel, United States,
• Organes Aucun
• Spécialités Aucun

Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA This trial is a 6-week, double-blind, placebo-controlled, randomized-withdrawal, multicenter study of safety and efficacy of JZP-110 in the treatment of excessive sleepiness in adult subjects with OSA.

• Pays Finland, France, Germany, Sweden, United States,
• Organes Aucun
• Spécialités Aucun

Letrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation RATIONALE: Letrozole may prevent breast cancer in postmenopausal women with a BRCA1 or BRCA2 mutation. PURPOSE: This randomized phase III trial is studying letrozole to see how well it works compared with a placebo in preventing breast cancer in postmenopausal women with a BRCA1 or BRCA2 mutation.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Gelatin in ICU and Sepsis This prospective, double-blind randomized controlled trial evaluates the differences in terms of efficacy and safety of gelatin based resuscitation as compared to crystalloid based resuscitation in two parallel groups of patients with severe sepsis / septic shock.

• Pays Austria, Czech Republic, France, Germany, Hungary,
• Organes Aucun
• Spécialités Aucun

Curarisation and Intubation Conditions During Videolaryngoscopy With Glidescope Titanium In this prospective, randomized study, the investigators assess the intubation conditions during videolaryngoscopy with Glidescope Titanium whether patients receive (curare (Atracurium) group) or no (control group) within elective surgery patients with no difficult intubation prediction

• Pays France,
• Organes Aucun
• Spécialités Aucun